Requisition Number: STFR004434
Division/College: Bouve College of Health Sciences
Location: Boston Main Campus
Full-time/Part-time: Full Time
The Center for Drug Discovery, Northeastern University, is dedicated to discovering novel medications, developing technologies that increase the success of discovering new therapeutic agents, and training scientists in the multidisciplinary field of drug discovery. To help fulfill this mission, we seek a full-time Associate Research Scientist experienced in drug discovery synthetic chemistry and its applications to biological systems. This hands-on position is key to the Center’s activities for both translational science and for conducting pre-clinical research.
Under the direction of the Center’s Director, the candidate will independently design and synthesize novel compounds, develop novel and suitable synthetic routes for chemistry scaffolds leading to potent ligands, record, analyze, and interpret resulting data, organize the data into a form suitable for peer-reviewed publications, patent filing, new grant submissions and existing/funded grant reports, and plan future experimental approaches. As required, the candidate will also develop novel, economical, scalable and reproducible synthetic routes for the re-synthesis of key synthetic intermediates and lead compounds to facilitate further in vitro and in vivo testing. As a team player, he/she will be expected to actively participate in Center meetings and seminars, collaborate and work with the Center’s interdisciplinary teams. The incumbent should be highly motivational, and should be able to integrate in a team with multidisciplinary background. The incumbent will also be responsible for: training and supervising students and post-doctoral scientists; helping to set project goals and objectives; develop research protocols and experiments for applied research at an advanced level jointly developed with the CDD Director, including recommendations for future research projects.
Ph.D. in Chemistry and/or Chemical Biology with at least five years of work experience on performing medicinal chemistry, preferably experiments either independently or in collaboration with Supervisor/Director. The candidate must be able to undertake full-time research, together with scholarship and work independently on projects and tasks that are assigned by Supervisor/Director.
Special Additional Experience: Applicants should have a Ph.D. in chemistry with preferred experience and expertise in organic chemistry and medicinal chemistry. The applicant must have a proven track record of academic accomplishments in the form of peer-reviewed publications in reputable organic/medicinal chemistry journals and/or patent filings. The applicant must be skilled in NMR techniques (1H, 13C etc.) and proficient in purification techniques (Flash purification, HPLC, LCMS etc.). Knowledge of parallel synthesis techniques, solid-phase synthesis and microwave synthesis will be preferred. The applicant must have excellent communication and interpersonal skills and prior experience in a drug discovery setting and knowledge in grant writing and report preparation. Knowledge of good chemical and laboratory safety procedures is mandatory. The applicant must be a role model for graduate students and beginning level Post-docs, providing guidance in terms of work ethic, laboratory techniques, and ability to adhere to the Center for Drug Discovery and Northeastern University safety rules and production standards.
The Bouv College of Health Sciences at Northeastern University is one of nine colleges/schools at Northeastern University, and is a national model for education and research in the health, psychosocial and biomedical sciences. Comprised of three schools Nursing, Pharmacy and Health Professions over 2000 undergraduates and 2400 graduate students are enrolled in more than 30 degree-granting programs. Complementing our instructional programs, we house nine centers and institutes and the College successfully competes for NIH, NSF and foundation funding.
Northeastern University is on an exciting trajectory of growth and innovation. The University is a leader in inter-disciplinary research, urban engagement, experiential learning, and the integration of classroom learning with real-world experience. Northeastern University is home to 20,000 students and to the nations premier cooperative education program. The past decade has witnessed a dramatic increase in Northeasterns international reputation for research and innovative educational programs. A heightened focus on interdisciplinary research and scholarship is driving a faculty hiring initiative at Northeastern, advancing its position amongst the nations top research universities. Northeastern University is situated on the Avenue of the Arts in Bostons historic Back Bay, four blocks from the Longwood Medical Area, encompassing Harvard Medical School, Boston Childrens Hospital, Brigham & Womens Hospital, and Beth Israel Deaconess Medical Center, and eight blocks from the Boston Medical Center.
How to apply
To be considered for this position please visit our web site and apply on line at the following link: Careers@Northeastern
Northeastern University is an Equal Opportunity, Affirmative Action Educational Institution and Employer, Title IX University. Northeastern University particularly welcomes applications from minorities, women and persons with disabilities. Northeastern University is an E-Verify Employer.